Home > Publications


Table of contents
No headers
1. Johannes, T.W.∗, DeSieno, M.A∗, Griffin, B.M, Thomas, P.M., Kelleher, N.L., Metcalf, W.W., and Zhao, H.  Deciphering of the Late Biosynthetic Steps of Antimalarial Compound FR‐900098. Chemistry and Biology, 17, 57-64 (2010) PDF


2. Choi, Y.∗, Johannes, T.W.∗, Simurdiak, M., Shao, Z., Lu, H., and Zhao, H. Cloning and Heterologous Expression of the Spectinabilin Biosynthetic Gene Cluster from Streptomyces spectabilis. Molecular BioSystems, 6, 336-338 (2010) PDF


3. Nair, N.U., Shao, Z., DeSieno, M., Johannes, T.W., Zhao, H., Lee, T., Sullivan, R.P., McLachlan, M., Zhao, H. Towards the Cost‐effective Production of Antimalarial Drug FR‐900098 and Butanol. Proceedings of Foundations of Systems Biology (FOSBE), Denver, CO (2009) 


4. Eliot, A.C., Griffin, B.M., Thomas, P.M., Johannes, T.W., Kelleher, N.L., Zhao, H., and Metcalf, W.W. Cloning, expression, and biochemical characterization of Streptomyces rubellomurinus genes required for biosynthesis of antimalarial compound FR900098. Chemistry and Biology, 15, 765‐770 (2008) PDF



5. Mclachlan, M., Johannes, T.W., and Zhao, H. Further Improvement of Phosphite Dehydrogenase Thermostability by Saturation Mutagenesis. Biotechnology and Bioengineering, 99, 268‐274 (2008) PDF



6. Johannes, T.W., Woodyer, R.D., and Zhao, H. Efficient Regeneration of NADPH Using an Engineered Phosphite Dehydrogenase. Biotechnology and Bioengineering, 96, 18‐26 (2007) PDF



7. Johannes, T.W. and Zhao, H. Directed Evolution of Enzymes and Biosynthetic Pathways. Current Opinion in Microbiology, 9, 1‐7 (2006) PDF


8. Johannes, T.W., Woodyer, R.D., and Zhao, H. Directed Evolution of a Thermostable Phosphite Dehydrogenase for NAD(P)H Regeneration. Applied and Environmental Microbiology, 71, 5728‐5734 (2005) PDF



9. Johannes, T.W., Woodyer, R.D. and Zhao, H. “High Throughput Screening Methods for Oxidoreductases.” In Enzyme Assays: High‐throughput Screening, Genetic Selection and Fingerprinting, (J.L Reymond, Ed.) Wiley VCH‐Verlag GmbH, Weinheim, Germany, Chapter 3, pp. 77‐93 (2006)


10. Johannes, T.W., Simurdiak, M. and Zhao, H. “Biocatalysis.” In Encyclopedia of Chemical Processing, (S. Lee, ed.) Marcel Dekker, Inc., New York, NY, pp. 101‐110 (2006) PDF


11. Woodyer, R.D., Johannes, T.W., and Zhao, H. “Cofactor Regeneration for Biocatalytic Applications.” In Enzyme Technology, (A. Pandey, C. Webb, C. S. Soccol, and C. Larroche, Eds.) Chapter 5, pp. 83‐101, Asiatech Publishers, Inc., New Delhi, India (2004) PDF



Tag page
You must login to post a comment.